Dextroamphetamine can further be metabolized to form other metabolites, such as hippuric acid. Lisdexamfetamine is not metabolized by cytochrome P450 enzymes.
It is combined with racemic-amphetamine in the ADHD drug Adderall. It is the active metabolite of the recently introduced prodrug lisdexamfetamine, known by its
Filter by metabolite status (default all): ; HMDB . . Dasatinib, HMDB structure image ; HMDB . . Lisdexamfetamine
by E Comiran 2024 Cited by 29S.W. Boellner et al. Pharmacokinetics of lisdexamfetamine dimesylate and its active metabolite, d-amphetamine, with increasing oral doses of lisdexamfetamine
HYDROXYZINE LAMOTRIGINE LISDEXAMFETAMINE LITHIUM LORAZEPAM Bupropion and its metabolites (erythrohydrobupropion, threohydrobupropion
In this study, the lisdexamfetamine dimesylate prodrug was extensively metabolized to the pharmacologically active d-amphetamine (the primary metabolite) and d-amphetamine-derived metabolites. After oral administration of lisdexamfetamine dimesylate 70 mg, systemic exposure to intact lisdexamfetamine dimesylate was modest and almost 20-fold
Hydroxyzine, The serum concentration of dextroamphetamine, an active metabolite of Lisdexamfetamine, can be increased when used in combination with Hydroxyzine.
Metabolites (62 Compounds) in Human Urine. [Journal Article]. Methods Mol Lisdexamfetamine (LDX) is a prodrug that is enzymatically converted into
The half-life of Vyvanse can be broken down into its main ingredient, lisdexamfetamine, and its main metabolite, dextroamphetamine.
Comments
This is a situation where LESS revenge is probably more. I think donating $20K worth of chickens or goats to African farmers (delivered BEFORE Pred is told!) AND told he has to move out immediately plus leave the state within a month, might keep him from trying to involve law enforcement. Include the threat of serious penile shrinkage, and the fact that the couple (and others not revealed to him) will be monitoring him closely, to thwart much likelihood of him trying to attempt recrimination.
Not a bad little story, but taking a little longer in its execution could have upped the ante!
4*
Seriously, no woman unless eh is afflicted with a mental disorder, willingly has sex with her rapist.
Yes he threatened photos, but it was (supposedly) her husband having an affair (false), her heightened libido (usually opposite effect with menopause), getting gifts and companionship (all the holding hands, jokes, finner conversation once a month), and her compartmentalization, that made her WANT yo have sex with her rapist. I call bs. That is nonsensical.
That being said Karen does comes off as a bit of a nutjob. She tessl Darren sex with him is not very good, and well she enjoys it because she feels she had to go through with it so she might was well enjoy it, but hey with time she can train Darren to be as good as her husband. But... she tells her husband the sex was sh$t, Darren is terrible and selfish, but she is really horny and since he was a friend (hello freaking rapist is NOT you or your husband's friend!), she enjoyed his company, which bte apparently included intimacy as they schmooze around the hotel. Wtf? Maybe she is psychotic.
But the worst part, is Darren raped Karen, and nothing happened except for some revenge by the wife in making him have a junior roles in the company. Wtf? No police alerted. Wife doesn't wake up after the rape, even with the weak sauce blackmail threat, and get tested for date rape drugs (detectable as urine metabolites for up to 5 to 7 days afterwards, and if positive, she has Darren by the balls)? No rape kit. No telling her husband. Hubby trades up for a better job via his own blackmail (the letter) instead of getting justice for his wife and his marriage. Sheila isn't told, she learns from YouTube. Wtf?
Let's be brutally honest. Karen wanted to have an affair. Yes the first time when drugged and raped, she was blameless and raped. But she didn't get help. Didn't go to authorities. And it wasn't the blackmail sex threat driving her. It was that Darren has already convinced her that the MC was having an affair while traveling up north. He was too tired on Friday night to attend to her sexually. So heaven forbid, only sex two or three times a week. And she was horny due to menopause (a laughable LW trope btw). She was pissed, wanted revenge, was sick of being neglected (though engineered by Darren), and wanted to have sex with another man. The blackmail and rape is only tossed in yo give a way back to a RAAC.
Meh. 3.5 stars. Not one of the author's better stories. Didn't mind the restaurant scene, but so much of the rest of it was nonsensical or nauseating.